Yes — and that’s one of the biggest strengths of this plugin.
You can target students based on:

• Group membership
• Individual selection
• Course enrollment
• Course progress (not started, in progress, completed)
• Assignment submissions (submitted/not submitted/late)
• Quiz performance (passed/failed/not attempted)
• Custom score thresholds

You even get exclusion options like:

• Exclude admins and group leaders
• Exclude all group students (to reach only independent learners)

It gives you full control — no more “emailing everyone just to reach a few.”